Anion Titration Studies of Tetramide Compounds as A Potential Chromate Separation Materials
DOI:
https://doi.org/10.11113/jomalisc.v2.38Keywords:
Amide, anion, chromate, anion titration, anion bindingAbstract
This study describes the synthesis and characterization of two tetraamide compounds namely, 1,2-bis[N,N’-6-(4-pyridylmethylamido)pyridyl-2-carboxyamido]ethane (L1) and 1,2-bis[N,N’-6-(4-pyridylmethylamido)pyridyl-2-carboxyamido]propane (L2) which were prepared by reacting N-6-[(4-pyridylmethylamino)carbonyl]-pyridine-2-carboxylic acid methyl ester with ethane-1,2-diamine and propane-1,3-diamine, respectively. These types of compounds are commonly studied for anion separation materials due to their pre-organized structure that is readily intended to capture anion via hydrogen bonding. Characterization of L1 and L2 was conducted by Fourier Transform Infrared spectroscopy (FTIR), 1H and 13C Nuclear Magnetic Resonance (NMR). The structure conformation was supported by theoretical studies which were conducted through DFT analysis. Evaluation of the potential of these compounds to interact with chromate anions was investigated using the UV-Vis titration technique. The results showed that L1 has a good affinity towards chromate anions compared to L2. This result concluded that the utilization of smaller spacer units such as ethyl contributed to the ease of binding of a molecular host to chromate anions through NH amide binding pockets, compared to the use of a lengthier spacer.
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